Resignation Not acceptance issue

Hi Sir, I am completed 5 months in my current company but put Resignation paper but my company not accept my Resignation who's name is I-source infosystems pvt Ltd. And I am served 45 days notice period and my last working day is 9th dec. And my employer doing mentally harassment me. And say complete one year. And health is to weak because I am doing night shift from last 5 months please help me. What can I do regards the same. Regards Shalender Singh